Quick Answer: Where Does Sickle Cell Trait Come From?

Can a child have sickle cell trait if neither parent has it?

Your child would have to inherit two sickle cell genes to have sickle cell disease.

So if your child’s father does not have the sickle cell gene, your child can’t get sickle cell disease..

Where did sickle cell trait come from?

The origin of the mutation that led to the sickle-cell gene derives from at least four independent mutational events, three in Africa and a fourth in either Saudi Arabia or central India. These independent events occurred between 3,000 and 6,000 generations ago, approximately 70-150,000 years.

What blood type is sickle cell trait?

Examples: If one parent has sickle cell anemia (SS) and the other parent has normal (AA) blood, all of the children will have sickle cell trait.

Does sickle cell trait weaken your immune system?

Sickle cells can damage your spleen, the organ that helps fight germs as part of your immune system. That can make you more likely to get pneumonia and other infections.

Can sickle cell trait disappear?

This is called anemia and it does not go away. It is important for babies with sickle cell anemia to receive regular medical care. How common is sickle cell anemia? Sickle cell anemia affects both males and females.

How long can you live with sickle cell trait?

A published case study reports that patients with mildly symptomatic sickle cell disease (SCD) can exceed the U.S. median life expectancy of 47 years for patients with the disease if it is managed properly.

Can I donate plasma if I have sickle cell trait?

Sickle Cell: You may donate plasma or platelets if you have the sickle cell trait, but not whole blood.

What if one parent has sickle cell trait?

If one parent has sickle cell trait (HbAS) and the other has sickle cell anaemia (HbSS) there is a one in two(50%) chance that any given child will get sickle cell trait and a one in two chance that any given child will get sickle cell anaemia. No children will be completely unaffected.

Who carries the sickle cell trait?

Sickle cell trait (also known as being a carrier) occurs when a person has one gene for sickle hemoglobin and one gene for normal hemoglobin. Approximately one in ten African-Americans carries sickle cell trait. People who are carriers generally do not have any medical problems and lead normal lives.

Does sickle cell trait cause iron deficiency?

Sickle cell anemia (SCA) is an inherited disorder of hemoglobin synthesis that is characterized by life-long severe hemolytic anemia, attacks of pain crisis, and chronic organ system damage. A third of the hemolysis in SCA is intravascular and the resulting urinary losses of iron may lead to iron deficiency.

What vitamins are good for sickle cell trait?

Supplementing with vitamin A may help correct a deficiency. Antioxidant nutrients protect the body’s cells from oxygen-related damage. Many studies show that sickle cell anemia patients tend to have low blood levels of antioxidants, including carotenoids, vitamin A, vitamin E, and vitamin C, despite adequate intake.

Does having the sickle cell trait affect you?

Sickle cell trait is NOT a disease and will never turn into a disease. People with sickle cell trait usually do not have any health problems. However, under extreme conditions a person with sickle cell trait can experience some of the same problems as a person who has sickle cell disease.

Can you donate blood if you have sickle cell trait?

Is it safe for people with sickle cell trait to donate blood? Yes. If you have sickle cell trait, you are still are able to donate blood. There is no evidence to suggest that donating blood causes any additional risk of harm or injury to people with sickle cell trait.

Can you donate bone marrow if you have sickle cell trait?

People with sickle cell trait got the sickle cell gene from 1 parent but not both. Most people with sickle cell trait don’t have any symptoms of SCD. They can be blood, marrow and organ donors.

Can sickle cell trait cause breathing problems?

People with sickle cell anemia can develop high blood pressure in their lungs. This complication usually affects adults. Shortness of breath and fatigue are common symptoms of this condition, which can be fatal.

Does sickle cell trait make you tired?

Fatigue is a common symptom associated with sickle cell disease. Due to the smaller size of our red blood cells, we cannot carry as much oxygen as those with healthier red blood cells. This leads to a lack of oxygen in our bodies and, ultimately, fatigue.

Can sickle cell patients Fly?

People with sickle-cell trait are at risk if they fly in unpressurized aircraft, which are used for many local air services. Those with sickle-cell haemoglobin C disease should avoid air travel even in pressurized aircraft.

Can a white person have sickle cell trait?

Sickle cell trait is an inherited blood disorder that affects 1 million to 3 million Americans and 8 to 10 percent of African Americans. Sickle cell trait can also affect Hispanics, South Asians, Caucasians from southern Europe, and people from Middle Eastern countries.

How is sickle cell trait diagnosed?

For older children and adults, a doctor can diagnose sickle cell trait with a simple blood test. This involves taking a blood sample from the end of the finger or a vein in the arm and sending it to a laboratory for analysis. Insurance often covers testing for sickle cell trait.